Penicillin, Its Practical Application




Butterworth, And Co. (Publishers), Ltd., Bell Yard, Temple Bar.






Under the general editorship of professor sir alexander fleming m.b., b.s., f.r.c.p., f.r.c.s., f.r.s. professor of bacteriology in the university of london, st. mary's hospital, london. (butterworths medical publications)

Item Description

FIRST EDITION. 8vo. 8.75 X 5.75 inches. x + [ii] + 380 pp. Bound in original green cloth, gilt. Extremities worn and spine a little sunned. Minor spotting of edges, but otherwise a very good clean copy. Long dedicatory inscription of 1947 to Miss C. A. Johnson, S.R.N. in recognition of her work 'during severe wintry conditions in the Spring Term 1947,' signed by William Ingram Headmaster of Kimbolton School (1913-47). The School, now an independent co-educational boarding school, was founded c.1600 and until 1949 was known as Kimbolton Grammar School (for over 300 boys). (Printing and the Mind of Man, 420). Illustrated by 59 black and white photographs and by diagrams in text. A work which marked a medical milestone, being a systematic survey of the development, preparation and practical application of the antibacterial properties of penicillin, published soon after it had become the world's first potent antibiotic (A second edition was published in 1950). The introduction of this revolutionary drug during the war transformed medical practise and brought many potentially fatal conditions and diseases under control for the first time. The book contains 27 papers, with two contributions by Fleming himself, including an account of the history and development of penicillin. Its antibacterial properties, discovered accidentally, were first published by Fleming in a paper of 1929 and it was sporadically used by him as a local antiseptic. It was not, however, developed into an effective and practical drug until the researches of Howard Florey and Ernst Boris Chain at Oxford led to the successful mass production of penicillin in the USA. All three shared the Nobel prize for medicine in 1945. Alexander Fleming (1881-1955) served in the RAMC during the First World War, researching the healing of war wounds. At the time of his first isolation of penicillin he was Professor of Bacteriology at the University of London.

[Stock No. 27536]

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